Szczegóły obiektu: Development and study of perspective clinical properties of biologically active matrix composed of decellularized lyophilized human amniotic membrane in combination with platelet-derived growth factors and hyaluronic acid

Instytucja dostarczająca:Akademicka Platforma Czasopism

Opis

Tytuł:
Development and study of perspective clinical properties of biologically active matrix composed of decellularized lyophilized human amniotic membrane in combination with platelet-derived growth factors and hyaluronic acid
Twórca:
Vyshnevska, H. O.;
Kakabadze, Z. Sh.;
Schnayder, S. A.;
Tiron, O. I.;
Dzygal, O. F.
Opis:
Nowadays the development of novel biomaterials which would promote tissue lesions regeneration is one of the crucial tasks of regenerative medicine. In the current research we developed a biological active membrane composed of decellularized, lyophilized human amniotic membrane in combination with growth factors of platelet-rich plasma (PRP) and hyaluronic acid. On the basis of histological examination, scanning electron microscopic examination and DNA content analyses it was drawn a conclusion that Sodium Dodecyl Sulfate (SDS) (Sigma) solution and 1% Triton X-100 solution completely remove all existing cells of placenta and chorionic-amniotic membrane without impairment of their structure. After the processes of decellularization and lyophilization the DNA content was less than 2%. The PRP growth factors as the components biological matrix provide faster regeneration. The latter are fixed on the surface of cellular structure of decellularized, lyophilized human amniotic membrane by the reservoir of gelatinous hyaluronic acid
Dostępność obiektu:
Dostęp otwarty
Prawa:
Prawa autorskie (c) 2019 © The Author (s)
Data:
2019.11.29
Typ:
info:eu-repo/semantics/article;
info:eu-repo/semantics/publishedVersion
Język:
angielski
Źródło:
Journal of Education, Health and Sport; Vol. 9 No. 11 (2019); 410-418;
Journal of Education, Health and Sport; Tom 9 Nr 11 (2019); 410-418;
2391-8306
Format:
application/pdf
Wydawca:
Nicolaus Copernicus University, Toruń, Poland
Relacja: https://apcz.umk.pl/JEHS/article/view/JEHS.2019.09.11.038/26538
Temat i słowa kluczowe:
amniotic membrane;
growth factors;
hyaluronic acid;
morphology;
scanning electron microscopy
Identyfikator: https://apcz.umk.pl/JEHS/article/view/JEHS.2019.09.11.038
Dostawca danych:
Akademicka Platforma Czasopism

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Szczegóły obiektu: Development and study of perspective clinical properties of biologically active matrix composed of decellularized lyophilized human amniotic membrane in combination with platelet-derived growth factors and hyaluronic acid

Opis

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