Opis

• Tytuł:
  Inhibitors of bacterial and plants urease
• Twórca:
  Macegoniuk, Katarzyna
• Współtwórca:
  Department of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław;
  katarzyna.macegoniuk@pwr.wroc.pl
• Opis:
  Urease is an important virulence factor for Helicobacter pylori and Proteus mirabilis as well as in environmental transformations of certain nitrogenous compounds. Urea hydrolysis caused by these microorganisms leads to increased pH and ammonia toxicity and enables bacterial colonization of the human gastric mucosa and urinary tract formation of struvite and carbonate-apatite stones. Due to the possibility of medical applications the development of novel, selective and efficient classes of urease inhibitors which satisfy the low toxicity requirement for human health and have low environmental impact is necessary. In this article are described the various urease inhibitors used so far by researchers, especially in the last few years.
• Dostępność obiektu:
  Dostęp otwarty
• Prawa:
  This content is open access.
• Data:
  2015.06.17;
  2013.12.31
• Format:
  application/pdf
• Wydawca:
  Versita
• Relacja:
  Folia Biologica et Oecologica;9
• Temat i słowa kluczowe:
  urea;
  urease;
  inhibitor;
  ulcer disease;
  kidney stones
• Identyfikator: http://hdl.handle.net/11089/9894 ;
  10.2478/fobio-2013-0004
• Dostawca danych:
  Repozytorium Uniwersytetu Łódzkiego
• Czy mogę z tego obiektu skorzystać?:
  poproś o pozwolenie
• Rodzaj zawartości:
  pozostałe