Opis

• Tytuł:
  What kind of therapeutic solutions for Graves’ disease does modern medicine propose? - a review of the literature
• Twórca:
  Woś, Natalia;
  Szala-Czerwonka, Karolina;
  Rejmer, Adrian;
  Rojek, Katarzyna;
  Bednarz, Lucjan;
  Wijas, Karolina;
  Bialic, Kinga;
  Bakalarczyk, Rafał;
  Bialic, Artur;
  Majewski, Paweł
• Opis:
  Background: Graves' disease is responsible for 60-80% causes of hyperthyreosis. An important role in the pathogenesis is played by anti-TSHR immunoglobulins (TRAb), that stimulate TSH receptors leading to excessive hormone synthesis and release by the gland. The aim of the study: This study was designed to summarise the current state of knowledge on the diagnosis, pathogenesis and methods of treatment used for Graves' disease. Materials and methods: We reviewed the literature available in the PubMed database using the following keywords: "Graves' disease", "Graves' pathogenesis", "Graves' diagnosis", "Graves' treatment”. Results: Graves' disease develops as a result of as well genetic as environmental factors. The diagnosis is based on physical examination, and laboratory & imaging studies. Several therapeutic options are currently used. Pharmacotherapy with thyreostatics is used either as a stand-alone method or as a preparation for a radical treatment - radioactive iodine ablation and thyroidectomy, which is the surgical removal of the gland. The treatment form is recommended to be selected individually depending on each patient, indications and co-morbidities. Developing research into the etiology of the disease is an opportunity to develop newer and efficient methods of causal treatment.  Summary: Graves' disease is an autoimmune thyroid disorder with a multiple factor etiology. A variety of therapeutic approaches are currently used: treatment with antithyrodid drugs, radioactive iodine ablation and the surgical resection of the thyroid gland. A more detailed understanding of the mechanisms causing the development of the disease offers prospects for the creation of innovative and more efficient therapeutic modalities.
• Dostępność obiektu:
  Dostęp otwarty
• Prawa: https://creativecommons.org/licenses/by-nc-sa/4.0 ;
  Prawa autorskie (c) 2023 Natalia Woś, Karolina Szala-Czerwonka, Adrian Rejmer, Katarzyna Rojek, Lucjan Bednarz, Karolina Wijas, Kinga Bialic, Rafał Bakalarczyk, Artur Bialic, Paweł Majewski
• Data:
  2023.05.20
• Typ:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Język:
  angielski
• Źródło:
  Journal of Education, Health and Sport; Vol. 32 No. 1 (2023); 31-46;
  Journal of Education, Health and Sport; Tom 32 Nr 1 (2023); 31-46;
  2391-8306
• Format:
  application/pdf
• Wydawca:
  Nicolaus Copernicus University, Toruń, Poland
• Relacja: https://apcz.umk.pl/JEHS/article/view/43716/35622
• Temat i słowa kluczowe:
  Graves' disease;
  Graves' pathogenesis;
  Graves' diagnosis;
  Graves' treatment
• Identyfikator: https://apcz.umk.pl/JEHS/article/view/43716
• Dostawca danych:
  Akademicka Platforma Czasopism
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