Opis

• Tytuł:
  Impact of Gonadotropin-releasing Hormone Analogue and Gender-affirming Hormone Therapy on Bone Mineral Density in Transgender Adolescents
• Twórca:
  Chuncia, Marta;
  Czyż, Witold;
  Kacperczyk, Julia;
  Arczewski, Filip;
  Dziedzic, Karol;
  Kulbacka, Julia;
  Wojszczyk, Maciej;
  Zys, Damian;
  Pasek, Piotr;
  Ryniecka, Julia
• Opis:
  Background: Sex hormones have a key impact on the development of the human body during puberty, including a significant influence on bone development - their shape, structure, length, and mineral density. Due to the growing number of transgender and gender diverse (TGD) adolescents and the increasing demand for gender-affirming hormone therapy (GAHT), there is rising curiosity about the impact of this therapy on the developing body of a young person.  Purpose: This review aims to summarize the latest scientific reports on the impact of gonadotropin-releasing hormone analogues (GnRHas) and GAHT on the bone mineral density (BMD) of transgender adolescents undergoing gender-changing therapies.  Findings: Low pretreatment BMD is more common among TGD adolescents than in the general population, and this is more prevalent in transgirls than in transboys. BMD Z-scores decline during treatment with GnRHas and respond differentially to GAHT. Regular follow-up and health advice are essential. Further long-term studies of the effects of these therapies on peak bone mass and future fracture risk are needed.
• Dostępność obiektu:
  Dostęp otwarty
• Prawa: https://creativecommons.org/licenses/by-nc-sa/4.0 ;
  Prawa autorskie (c) 2025 Marta Chuncia-Ileczko, Witold Czyż, Julia Kacperczyk, Filip Arczewski, Karol Dziedzic, Julia Kulbacka, Maciej Wojszczyk, Damian Zys, Piotr Pasek, Julia Ryniecka
• Data:
  2025.01.07
• Typ:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Język:
  angielski
• Źródło:
  Quality in Sport; Tom 37 (2025); 57200;
  Quality in Sport; Vol. 37 (2025); 57200;
  2450-3118
• Format:
  application/pdf
• Wydawca:
  University Center for Sports Research, Nicolaus Copernicus University, Torun, Poland
• Relacja: https://apcz.umk.pl/QS/article/view/57200/41030
• Temat i słowa kluczowe:
  transgender and gender diverse youth;
  puberty suppression;
  gonadotropin-releasing hormone analogue;
  gender-affirming hormone therapy;
  bone health;
  transgender and bone
• Identyfikator: https://apcz.umk.pl/QS/article/view/57200
• Dostawca danych:
  Akademicka Platforma Czasopism
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