Opis

• Tytuł:
  Cannabis in Acute Injury Rehabilitation: Analgesic Efficacy, Functional Outcomes and Dependency Risks
• Twórca:
  Polok, Sebastian;
  Talaska, Justyna;
  Wasilewska, Małgorzata;
  Pietrzak, Krzysztof;
  Demel, Karol
• Opis:
  Background: Musculoskeletal injury rehabilitation is challenged by inadequate pain management using opioids and NSAIDs, which pose risks of addiction, side effects, and delayed healing. Cannabis has emerged as a potential analgesic, yet its efficacy, safety, and impact on functional recovery in acute injuries remain unclear, particularly for athletes. Purpose of Research: To evaluate the role of cannabis in acute injury rehabilitation, focusing on analgesic efficacy, functional outcomes, addiction risks, and implications for athletic recovery. Materials and Methods: A systematic review of PubMed and Google Scholar (2015–present) identified 24 studies (RCTs, observational studies, meta-analyses) assessing cannabis in acute injury rehab. Inclusion criteria prioritized pain scores (VAS/NRS), functional metrics (mobility, strength), and dependency rates (CUDIT). Non-English articles and animal studies were excluded. Basic Results: Cannabis demonstrated moderate analgesic efficacy, with 30% pain reduction vs. placebo in acute musculoskeletal injuries. Low-dose THC matched opioid efficacy with fewer side effects, while CBD showed anti-inflammatory effects (22% IL-6 reduction). Functional improvements in mobility and therapy adherence were noted, but psychoactive effects (sedation, cognitive impairment) and a 10–15% cannabis use disorder (CUD) prevalence were reported. Discrepancies emerged between subjective pain relief and objective biomarkers. Conclusions: Cannabis may offer short-term analgesic and functional benefits in acute injury rehab but requires careful risk-benefit assessment due to addiction potential, cognitive side effects, and variable dosing responses. Standardized guidelines, athlete-specific protocols, and multidisciplinary monitoring are critical to optimize therapeutic outcomes. Future research should prioritize long-term safety, dosing standardization, and sport-specific functional impacts.
• Dostępność obiektu:
  Dostęp otwarty
• Prawa:
  Prawa autorskie (c) 2025 Sebastian Polok, Justyna Talaska, Małgorzata Wasilewska, Krzysztof Pietrzak, Karol Demel;
  https://creativecommons.org/licenses/by-nc-sa/4.0
• Data:
  2025.05.11
• Typ:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Język:
  angielski
• Źródło:
  Quality in Sport; Tom 41 (2025); 60152;
  Quality in Sport; Vol. 41 (2025); 60152;
  2450-3118
• Format:
  application/pdf
• Wydawca:
  University Center for Sports Research, Nicolaus Copernicus University, Torun, Poland
• Relacja: https://apcz.umk.pl/QS/article/view/60152/42490
• Temat i słowa kluczowe:
  Cannabis;
  THC;
  CBD;
  Acute injury;
  Rehabilitation;
  Analgesia;
  Addiction
• Identyfikator: https://apcz.umk.pl/QS/article/view/60152
• Dostawca danych:
  Akademicka Platforma Czasopism
• Czy mogę z tego obiektu skorzystać?:
  poproś o pozwolenie
• Rodzaj zawartości:
  teksty