Szczegóły obiektu: Turmeric: A Spice Modulating Immune Response and Combatting Cancer – literature overview

Instytucja dostarczająca:Akademicka Platforma Czasopism

Opis

Tytuł:
Turmeric: A Spice Modulating Immune Response and Combatting Cancer – literature overview
Twórca:
Anna;
Mazur, Bartosz;
Stachyrak, Karol;
Mika, Dawid;
Kłos, Aleksandra;
Turek, Kamila;
Lambach, Maciej;
Pawlicki, Mateusz;
Mazurek, Aleksandra;
Wilanowska, Wiktoria
Opis:
Introduction Curcumin, the active ingredient in turmeric, is gaining increasing attention due to its potential health benefits, especially in the context of its immunomodulatory and anticancer properties. Aim of the study The aim of this review was to discuss recent findings regarding the impact of curcumin on the immune system and its potential applications in anticancer therapy. Materials and methods The paper was created based on the Pubmed and Scholar database. The literature was reviewed using the keywords: „curcumin”, „immunomodulatory effects”, „cytokines”, „anticancer”, „apoptosis”, „cell proliferation”, „radiosensitizing”. Results Studies have confirmed that curcumin, especially in the form of nanocurcumin, exhibits significant immunomodulatory effects. It reduces the number of Th17 cells, increases Treg cells, and regulates the expression of pro-inflammatory cytokines, which is crucial in controlling autoimmune reactions. Furthermore, it demonstrates anticancer activity by inhibiting the growth of cancer cells, stimulating apoptosis, and enhancing the effectiveness of anticancer therapy. Conclusions Despite promising results, further research on the safety of curcumin therapy, particularly in the long term, is essential. Limitations associated with bioavailability and pharmacokinetics suggest the need for the development of formulations with increased bioavailability to maximize the potential benefits of curcumin in the treatment of various disorders.
Object availability:
Dostęp otwarty
Prawa:
Prawa autorskie (c) 2024 Anna Greguła, Bartosz Mazur, Karol Stachyrak, Dawid Mika, Aleksandra Kłos, Kamila Turek, Maciej Lambach, Mateusz Pawlicki, Aleksandra Mazurek, Wiktoria Wilanowska;
https://creativecommons.org/licenses/by-nc-sa/4.0
Date:
2024.02.16
Typ:
info:eu-repo/semantics/article;
info:eu-repo/semantics/publishedVersion
Language:
angielski
Źródło:
Journal of Education, Health and Sport; Vol. 60 (2024); 221-238;
Journal of Education, Health and Sport; Tom 60 (2024); 221-238;
2391-8306
Format:
application/pdf
Wydawca:
Nicolaus Copernicus University, Toruń, Poland
Relacja: https://apcz.umk.pl/JEHS/article/view/48310/37675
Temat i słowa kluczowe:
curcumin;
immunomodulatory effects;
cytokines;
anticancer;
apoptosis;
cell proliferation;
radiosensitizing
Identyfikator: https://apcz.umk.pl/JEHS/article/view/48310
Data provider:
Akademicka Platforma Czasopism

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