Opis

• Tytuł:
  Understanding and Managing Atopic Dermatitis: Insights into Pathogenesis and Treatment Strategies
• Twórca:
  Szewczyk, Kamila;
  Szewczyk, Bartlomiej;
  Pytel, Paulina;
  Krzesłowska, Wiktoria Julia;
  Hołownia, Weronika;
  Wiśniewski, Szymon
• Opis:
  Background: Atopic dermatitis (AD), also known as atopic eczema, is a common, chronic, non-infectious, relapsing-remitting inflammatory skin disease with increasing incidence globally. It results from a complex interaction of immune dysregulation, genetic mutations, and environmental factors, causing severe itchy skin lesions. AD affects 10-20% of children and 2-10% of adults in industrialized countries and often precedes other atopic diseases such as asthma. Aim of the Study: This study aims to summarize the current knowledge on atopic dermatitis, including its epidemiology, etiology, and treatment methods. Materials and Methods: A literature review was conducted using the PubMed database with keywords: "atopic dermatitis," "atopic eczema," "JAK inhibitors," "calcineurin inhibitors," and "AD systematic treatment." Conclusion: AD is a multifactorial disease involving epidermal barrier defects, genetic predispositions, and immune dysregulation. Effective management requires a combination of topical and systemic therapies. First-line treatments include emollients and topical corticosteroids, with newer options like phosphodiesterase inhibitors, JAK inhibitors, and biologics offering promising results. This study provides a comprehensive overview of AD, emphasizing the need for a multifaceted treatment approach.
• Dostępność obiektu:
  Dostęp otwarty
• Prawa:
  Prawa autorskie (c) 2024 Kamila Szewczyk, Bartlomiej Szewczyk, Paulina Pytel, Wiktoria Julia Krzesłowska, Weronika Hołownia, Szymon Wiśniewski;
  https://creativecommons.org/licenses/by-nc-sa/4.0
• Data:
  2024.09.30
• Typ:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Język:
  angielski
• Źródło:
  Quality in Sport; Tom 22 (2024); 55014;
  Quality in Sport; Vol. 22 (2024); 55014;
  2450-3118
• Format:
  application/pdf
• Wydawca:
  University Center for Sports Research, Nicolaus Copernicus University, Torun, Poland
• Relacja: https://apcz.umk.pl/QS/article/view/55014/39881
• Temat i słowa kluczowe:
  atopic dermatitis;
  immune dysregulation;
  JAK inhibitors;
  calcineurin inhibitors;
  atopic dermatitis treatment
• Identyfikator: https://apcz.umk.pl/QS/article/view/55014
• Dostawca danych:
  Akademicka Platforma Czasopism
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