Szczegóły obiektu: Abnormal sphingolipid world in inflammation specific for lysosomal storage diseases and skin disorders.

Instytucja dostarczająca:Repozytorium Instytutu Biochemii i Biofizyki Polskiej Akademii Nauk

Opis

Title:
Abnormal sphingolipid world in inflammation specific for lysosomal storage diseases and skin disorders.
Creator:
Moskot, Marta;
Bocheńska, Katarzyna;
Jakóbkiewicz-Banecka, Joanna;
Banecki, Bogdan;
Gabig-Cimińska, Magdalena
Description:
Research in recent years has shown that sphingolipids are essential signalling molecules for the proper biological and structural functioning of cells. Long-term studies on the metabolism of sphingolipids have provided evidence for their role in the pathogenesis of a number of diseases. As many inflammatory diseases, such as lysosomal storage disorders and some dermatologic diseases, including psoriasis, atopic dermatitis and ichthyoses, are associated with the altered composition and metabolism of sphingolipids, more studies precisely determining the responsibilities of these compounds for disease states are required to develop novel pharmacological treatment opportunities. It is worth emphasizing that knowledge from the study of inflammatory metabolic diseases and especially the possibility of their treatment may lead to insight into related metabolic pathways, including those involved in the formation of the epidermal barrier and providing new approaches towards workable therapies.
Object availability:
Dostęp otwarty
Date:
2018
Type:
Article;
PeerReviewed
Language:
angielski
Format:
application/pdf
Publisher:
MDPI
Relation: http://eprints.ibb.waw.pl/1688 ;https://www.mdpi.com/1422-0067/19/1/247
Subject:
Q Science (General)
Identifier: http://eprints.ibb.waw.pl/1688/1/Paper_IJMS_2018.pdf ;
Moskot, Marta and Bocheńska, Katarzyna and Jakóbkiewicz-Banecka, Joanna and Banecki, Bogdan and Gabig-Cimińska, Magdalena (2018) Abnormal sphingolipid world in inflammation specific for lysosomal storage diseases and skin disorders. International Journal of Molecular Sciences, 19 (1). ISSN 1422-0067
Data provider:
Repozytorium Instytutu Biochemii i Biofizyki Polskiej Akademii Nauk

Podobne obiekty

Abnormal sphingolipid world in inflammation specific for lysosomal storage diseases and skin disorders.

Twórca:Moskot, Marta | Bocheńska, Katarzyna | Jakóbkiewicz-Banecka, Joanna | Banecki, Bogdan | Gabig-Cimińska, Magdalena

Data:2018

Rodzaj zawartości:pozostałe

Use of cytokine mix-, imiquimod-, and serum-induced monoculture and lipopolysaccharide- and interferon gamma-treated co-culture to establish in vitro psoriasis-like inflammation models

Twórca:Bocheńska, Katarzyna | Moskot, Marta | Gabig-Cimińska, Magdalena

Data:2021

Rodzaj zawartości:pozostałe

Unbalanced sphingolipid metabolism and its implications for the pathogenesis of psoriasis

Twórca:Bocheńska, Katarzyna | Gabig-Cimińska, Magdalena

Data:2020

Rodzaj zawartości:pozostałe

Impact of isoflavone genistein on psoriasis in in vivo and in vitro investigations

Data:2021

Rodzaj zawartości:pozostałe

Nonsteroidal anti-inflammatory drugs modulate cellular glycosaminoglycan synthesis by affecting EGFR and PI3K signaling pathways

Data:2017.02.27

Rodzaj zawartości:pozostałe

Factors and processes modulating phenotypes in neuronopathic lysosomal storage diseases

Data:2013

Rodzaj zawartości:pozostałe

Cellular and gene expression response to the combination of genistein and kaempferol in the treatment of mucopolysaccharidosis type I

Data:2022

Rodzaj zawartości:pozostałe

Simultaneous siRNA-mediated silencing of pairs of genes coding for enzymes involved in glycosaminoglycan synthesis

Twórca:Dziedzic, Dariusz | Narajczyk, Magdalena | Gabig-Cimińska, Magdalena | Jakóbkiewicz-Banecka, Joanna

Data:2012

Rodzaj zawartości:pozostałe

Federacja Bibliotek Cyfrowych

Szczegóły obiektu: Abnormal sphingolipid world in inflammation specific for lysosomal storage diseases and skin disorders.

Opis

Podobne obiekty