Opis

• Tytuł:
  Unveiling the Potential of Gut Microbiota: Promising Approaches to Treat Drug-Resistant Epilepsy
• Twórca:
  Domańska, Natalia;
  Bojarska, Małgorzata;
  Bogucka, Julia;
  Brzyska, Anna;
  Kosowska, Michalina;
  Piecewicz-Szczęsna, Halina
• Opis:
  Introduction: Epilepsy is a chronic, non-infectious disease of the brain. Data shows that even 70 million people worldwide suffer from it and one-third of them fail to control it with anti-epileptic drugs. The gut microbiota has an impact on the course of the disease. The microbiota mediates between the gastrointestinal system and the central nervous system.Purpose: The aim of the work is to analyse how modification of the gut microbiota affects patients with drug-resistant epilepsy.Material and method: In December 2023, an extensive search was conducted and articles found in the Medline (PubMed) databases were selected by using the following keywords: drug-resistant epilepsy, gut microbiota, gut-brain axis, ketogenic diet, probiotics, faecal microbiota transplantation, to focus on recent developments and advancements in the field, the search was limited to articles published between 2017 and 2023.Conclusions: The intestinal microbiota in drug-resistant epilepsy (DRE) patients differs from that of healthy individuals or drug-sensitive epilepsy patients. Acknowledging the presence of the gut-brain axis and its impact on the central nervous system, we can view altering the flora as a potential therapeutic approach for DRE patients. The ways in which microbiota changes have been confirmed by research include: ketogenic diet, antibiotics, probiotics and fecal microbiota transplantation (FMT). Modifying the microbiota through these mentioned methods is all promising for treating DRE.
• Dostępność obiektu:
  Dostęp otwarty
• Prawa: https://creativecommons.org/licenses/by-nc-sa/4.0 ;
  Prawa autorskie (c) 2024 Natalia Domańska, Małgorzata Bojarska, Julia Bogucka, Anna Brzyska, Michalina Kosowska, Halina Piecewicz-Szczęsna
• Data:
  2024.10.14
• Typ:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Język:
  angielski
• Źródło:
  Quality in Sport; Tom 26 (2024); 55121;
  Quality in Sport; Vol. 26 (2024); 55121;
  2450-3118
• Format:
  application/pdf
• Wydawca:
  University Center for Sports Research, Nicolaus Copernicus University, Torun, Poland
• Relacja: https://apcz.umk.pl/QS/article/view/55121/40021
• Temat i słowa kluczowe:
  drug-resistant epilepsy;
  gut-brain axis;
  ketogenic diet;
  probiotics;
  faecal microbiota transplantation;
  gut microbiota
• Identyfikator: https://apcz.umk.pl/QS/article/view/55121
• Dostawca danych:
  Akademicka Platforma Czasopism
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