Opis

• Tytuł:
  The Influence of the Gut Microbiome on the Pathogenesis of Asthma: A Review of Current Research and Therapeutic Options
• Twórca:
  Feret, Dominik Maciej;
  Zapasek, Daniel;
  Szczepański, Michał;
  Kuliga, Marcin;
  Bajak, Mateusz;
  Słowik, Julia;
  Inglot, Julia;
  Inglot, Jadwiga;
  Mamczur, Maciej;
  Sowa, Damian
• Opis:
  Introduction and purpose: Asthma is a chronic inflammatory disease of the airways. Its pathogenesis may be linked to the gut microbiome, which plays a key role in the immune system. This review analyzes current evidence regarding the influence of the gut microbiome on asthma development, particularly in the context of the gut-lung axis. The aim of this paper is to assess the current therapeutic possibilities for asthma based on the modulation of the gut microbiota. Materials and methods: The literature review includes articles from scientific databases (PubMed), selected for their citation impact and relevance to the topic under analysis. Results: The gut microbiota affects immune balance by producing short-chain fatty acids (SCFAs) and other metabolites that modulate the body’s inflammatory response. Gut dysbiosis may contribute to the development of asthma. The use of probiotics, prebiotics, and a fiber-rich diet has shown beneficial effects in reducing inflammation in asthma. Fecal microbiota transplantation (FMT) may represent a future therapeutic approach, though further clinical research is required. Conclusion: Modulation of the gut microbiota is a promising support in asthma therapy. A personalized treatment approach based on the patient's microbiota profile could potentially improve disease control and reduce the reliance on steroids in the future.
• Dostępność obiektu:
  Dostęp otwarty
• Prawa: https://creativecommons.org/licenses/by-nc-sa/4.0 ;
  Prawa autorskie (c) 2024 Dominik Maciej Feret, Daniel Zapasek, Michał Szczepański, Marcin Kuliga, Mateusz Bajak, Julia Słowik, Julia Inglot, Jadwiga Inglot, Maciej Mamczur, Damian Sowa
• Data:
  2024.12.16
• Typ:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Język:
  angielski
• Źródło:
  Quality in Sport; Tom 35 (2024); 56359;
  Quality in Sport; Vol. 35 (2024); 56359;
  2450-3118
• Format:
  application/pdf
• Wydawca:
  University Center for Sports Research, Nicolaus Copernicus University, Torun, Poland
• Relacja: https://apcz.umk.pl/QS/article/view/56359/40706
• Temat i słowa kluczowe:
  asthma;
  gut microbiota;
  gut-lung axis;
  probiotics;
  prebiotics;
  fiber diet;
  personalised medicine;
  fecal microbiota transplantation
• Identyfikator: https://apcz.umk.pl/QS/article/view/56359
• Dostawca danych:
  Akademicka Platforma Czasopism
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