Description

• Title:
  Alachlor oxidation by the filamentous fungus Paecilomyces marquandii
• Creator:
  Słaba, Mirosława;
  Szewczyk, Rafał;
  Piątek, Milena Adela;
  Długoński, Jerzy
• Contributor:
  Department of Industrial Microbiology and Biotechnology, Faculty of Biology and Environmental Protection, University of Łódź
• Description:
  Alachlor, a popular chloroacetanilide herbicide, can be a potential health risk factor. Soil microorganisms are primarily responsible for conversion and migration of alachlor in natural environment, but knowledge concerning alachlor biodegradation is not complete. Therefore, we studied the ability of Paecilomyces marquandii, soil fungus tolerant to heavy metals, to eliminate alachlor and proposed a new pathway of its transformation. After 7 days of incubation only 3.3% of alachlor was detected from an initial concentration 50 mg L-1 and 20.1% from a concentration 100 mg L-1. The qualitative IDA LC-MS analysis showed the presence of ten metabolites. All of them were dechlorinated mainly through oxidation, but also reductive dechlorination was observed. The main route of alachlor conversion progressed via N-acetyl oxidation resulting in the formation of mono-, di- and trihydroxylated byproducts. N-acetyl oxidation as a dominant route of alachlor metabolism by fungi has not been described so far. The toxicity of alachlor tested with Artemia franciscana did not increase after treatment with P. marquandii cultures. Paecilomyces marquandii strain seems to be an interesting model for the research on alachlor conversion by soil microscopic fungi, due to its dechlorination and hydroxylation ability as well as high tolerance to heavy metals.;
  Grant of the National Centre for Science in Cracow, Poland, No UMO-2011/01/B/NZ9/02898
• Object availability:
  free access
• Rights:
  Uznanie autorstwa-Użycie niekomercyjne-Bez utworów zależnych 3.0 Polska;
  http://creativecommons.org/licenses/by-nc-nd/3.0/pl
• Data:
  2015.06.16;
  2013.06.24
• Typ:
  Article
• Język:
  English
• Format:
  application/pdf
• Wydawca:
  Elsevier Science Limited
• Relacja:
  Journal of Hazardous Materials;261 (2013)
• Temat i słowa kluczowe:
  biodegradation;
  lc-ms/ms;
  fungi;
  pesticides;
  alachlor;
  pathways;
  biotransformation;
  Paecilomyces marquandii;
  toxicology
• Identyfikator:
  1873-3336;
  http://hdl.handle.net/11089/9781 ;
  10.1016/j.jhazmat.2013.06.064
• Dostawca danych:
  Repozytorium Uniwersytetu Łódzkiego
• Can I use it?:
  check license
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