Object's details: Association of prenatal sex steroid exposure estimated by the digit ratio (2D:4D) with birth weight, BMI and muscle strength in 6- to 13- year-old Polish children

Provider:Repozytorium Uniwersytetu Łódzkiego

Description

Title:
Association of prenatal sex steroid exposure estimated by the digit ratio (2D:4D) with birth weight, BMI and muscle strength in 6- to 13- year-old Polish children
Creator:
Sitek, Aneta;
Kobus, Magdalena;
Rosset, Iwona;
Pruszkowska-Przybylska, Paulina;
Żądzińska, Elżbieta
Contributor:
Department of Anthropology, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland;
Biological Anthropology and Comparative Anatomy Research Unit, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia;
magdalena.kobus@biol.uni.lodz.pl
Description:
Objectives The aim of this paper was to provide evidence for the impact of prenatal sex steroid exposure on prenatal and postnatal body size parameters, and muscle strength in children. Methods The following anthropometric data were studied in a group of 1148 children (536 boys and 612 girls) aged 6–13 years: the 2D:4D digit ratio, birth weight and length, and birth head and chest circumference. Postnatal parameters (6–13 years) included body weight and height, BMI, waist and hip circumference, WHR, as well as grip strength in both hands. All parameters that required it were adjusted for sex and gestational or chronological age. A general linear model, Pearson’s correlation, t-statistics and Cohen’s Δ were used in statistical analysis. Results Among birth size parameters, only birth weight was significantly negatively correlated with the 2D:4D digit ratio in children. Higher (feminized) digit ratios were significantly correlated with postnatal parameters such as body weight, BMI, and waist and hip circumference (positively), as well as hand grip strength–a proxy for muscular strength (negatively). Conclusion Problems with maintaining adequate body size parameters and muscle strength may be programmed in fetal life and predicted on the basis of the 2D:4D digit ratio. Body weight at birth and in early ontogenesis are additive correlates of the 2D:4D ratio. The present findings suggest that the 2D:4D digit ratio is related to postnatal phenotypes such as birth weight, overweight, and obesity as well as muscle strength in 6–13-year-old children of both sexes.
Object availability:
free access
Rights:
Uznanie autorstwa 4.0 Międzynarodowe;
http://creativecommons.org/licenses/by/4.0
Date:
2021.10.13;
2021
Type:
Article
Language:
English
Format:
application/pdf
Publisher:
Public Library of Science
Relation:
PLoS ONE;16(10)
Subject:
Birth weight;
Hand strength;
Children;
Steroids;
Hands;
Hip;
Physiological parameters;
Type 2 diabetes risk
Identifier:
Kobus M, Sitek A, Rosset I, Pruszkowska–Przybylska P, Żądzińska E (2021) Association of prenatal sex steroid exposure estimated by the digit ratio (2D:4D) with birth weight, BMI and muscle strength in 6- to 13-yearold Polish children. PLoS ONE 16(10): e0258179. https://doi.org/10.1371/journal.pone.0258179;
http://hdl.handle.net/11089/39376 ;
1932-6203;
10.1371/journal.pone.0258179
Data provider:
Repozytorium Uniwersytetu Łódzkiego

Similar objects

Association of prenatal sex steroid exposure estimated by the digit ratio (2D:4D) with birth weight, BMI and muscle strength in 6- to 13- year-old Polish children

Creator:Sitek, Aneta | Kobus, Magdalena | Rosset, Iwona | Pruszkowska-Przybylska, Paulina | Żądzińska, Elżbieta

Date:2021.10.13 | 2021

Type:image

The role of flozins in managing cardiovascular risk in patients with type 2 diabetes - narrative review

Date:2024.09.30

Type:text

Type 2 diabetes - factors of occurrence and its complications

Date:2023.03.21

Type:text

Pioglitazone - the forgotten drug with multidirectional action

Creator:Aab, Arkadiusz | Zarańska, Julia

Date:2023.04.25

Type:text

GLP-1 Receptor Agonists: Therapeutic Benefits in Renal Function, Cardiovascular Risk, and Physical Activity - A Systematic Review

Date:2025.05.09

Type:text

The Impact of Puberty Timing on Future Metabolic and Hormonal Disorder Risk

Date:2025.06.03

Type:text

Pathophysiological association of expression hormone of adipose tissue omentin-1 and the degree of vascular remodeling of brachyocephalic vessels in persons with obesity and disorders of carbohydrate metabolism

Creator:Kulynych, Roman Leonidovich | Soloviuk, Olena Anatolyevna | Soloviuk, Oleksandr Olegovich

Date:2020.10.30

Type:text

Exposure to environmental tobacco smoke and children health

Creator:Tutka, Piotr | Wielosz, Marian | Zatoński, Witold

Date:2002

Type:other

Federacja Bibliotek Cyfrowych

Object's details: Association of prenatal sex steroid exposure estimated by the digit ratio (2D:4D) with birth weight, BMI and muscle strength in 6- to 13- year-old Polish children

Description

Similar objects