Object's details: The importance of stem cells in the treatment of type 1 diabetes, type 2 diabetes and diabetes complications: The importance of stem cells in diabetology

Provider:Akademicka Platforma Czasopism

Description

Title:
The importance of stem cells in the treatment of type 1 diabetes, type 2 diabetes and diabetes complications: The importance of stem cells in diabetology
Creator:
Kamińska, Monika;
Jasiewicz, Maria;
Miernik-Skrzypczak, Magdalena;
Spyra, Aleksandra;
Malicka, Marta;
Dąbrowska, Natalia;
Kozioł, Aleksandra;
Moczyróg, Katarzyna
Description:
Introduction and Purpose. Diabetes, characterized by hyperglycemia due to impaired insulin production or action, leads to significant complications like diabetic retinopathy (DR) and diabetic foot syndrome (DFS). Current treatments manage symptoms but do not fully address disease progression. Stem cells, with their regenerative potential and immunomodulatory properties, represent a promising avenue for treating diabetes and its complications. This study explores the use of stem cell therapy in managing type 1 and type 2 diabetes, DR, and DFS. Material and Method. The study reviewed existing literature on the application of stem cells in diabetes treatment. More than 30 articles addressing these issues were analyzed. They were found using the PubMed search engine, and the time frame of these publications covered the last 20 years. Results. Stem cells demonstrated significant potential in diabetes management. For type 1 diabetes, MSCs reduced inflammation, preserved pancreatic islet function, and decreased insulin requirements without major adverse effects. Pluripotent stem cells showed promise in islet transplantation, achieving stable glycemic control in clinical trials. In type 2 diabetes, stem cell therapy improved insulin sensitivity and reduced insulin dependency, with evidence of β-cell regeneration. Complications like diabetic foot ulcers and retinopathy also responded positively to stem cell treatments. MSCs improved wound healing by enhancing tissue regeneration and reducing inflammation, while retinal therapies showed promise in slowing disease progression and repairing damaged vasculature. Conclusions. Stem cell therapies offer a promising approach for diabetes and its complications, particularly for regenerative applications in DR and DFS. While initial results are encouraging, further large-scale studies are needed to optimize protocols, assess long-term safety, and establish standardized clinical applications.
Object availability:
free access
Rights: https://creativecommons.org/licenses/by-nc-sa/4.0 ;
Prawa autorskie (c) 2025 Monika Kamińska, Maria Jasiewicz, Magdalena Miernik-Skrzypczak, Aleksandra Spyra, Marta Malicka, Natalia Dąbrowska, Aleksandra Kozioł, Katarzyna Moczyróg
Date:
2025.01.14
Type:
info:eu-repo/semantics/article;
info:eu-repo/semantics/publishedVersion
Language:
English
Source:
Quality in Sport; Tom 37 (2025); 57420;
Quality in Sport; Vol. 37 (2025); 57420;
2450-3118
Format:
application/pdf
Publisher:
University Center for Sports Research, Nicolaus Copernicus University, Torun, Poland
Relation: https://apcz.umk.pl/QS/article/view/57420/41145
Subject:
stem cells;
diabetes mellitus type 1;
diabetes mellitus type 2;
diabetic retinopathy;
wound
Identifier: https://apcz.umk.pl/QS/article/view/57420
Data provider:
Akademicka Platforma Czasopism

Similar objects

The importance of stem cells in the treatment of type 1 diabetes, type 2 diabetes and diabetes complications: The importance of stem cells in diabetology

Date:2025.01.14

Type:text

Innovations in Pharmacotherapy of Diabetes: A Review of Latest Reports

Date:2025.07.08

Type:text

Challenges in managing de novo diabetes in adults: A case report of a 47 year old male

Date:2025.05.05

Type:text

Pathophysiological association of expression hormone of adipose tissue omentin-1 and the degree of vascular remodeling of brachyocephalic vessels in persons with obesity and disorders of carbohydrate metabolism

Creator:Kulynych, Roman Leonidovich | Soloviuk, Olena Anatolyevna | Soloviuk, Oleksandr Olegovich

Date:2020.10.30

Type:text

The role of the IRS1 gene (rs2943640) in the comorbid course of type 2 diabetes mellitus, obesity and arterial hypertension

Creator:Vivsiana, I. | Habor, H. | Marushchak, M.

Date:2021.01.29

Type:text

Poziom lęku u osób chorych na cukrzycę

Creator:Kocemba, Iwona

Date:2014.03.08 | 2004

Type:image

Glucagon-like peptide 1 receptor agonists in obesity treatment - a literature review

Date:2025.02.06

Type:text

Tirzepatide - role in obesity, health and physical wellness. Information overview

Date:2025.02.13

Type:text

Federacja Bibliotek Cyfrowych

Object's details: The importance of stem cells in the treatment of type 1 diabetes, type 2 diabetes and diabetes complications: The importance of stem cells in diabetology

Description

Similar objects