Description

• Title:
  Effect of glucagon-like peptide-1 (GLP-1) agonists on the example of semaglutide on the cardiovascular system and their role in the treatment of obesity.
• Creator:
  Pondel, Kamil;
  Kawałko, Kinga;
  Bielewicz, Krzysztof;
  Chmura, Anna;
  Karaś, Anna
• Description:
  Obesity nowadays affects an increasing number of people. We can talk about it when the patient's BMI is ≥ 30.0 kg/m² (BMI 25.0-29.9 kg/m² - overweight). While obesity in itself may not be a problem for people suffering from it, its complications can be global and sometimes pose a serious threat to health or even life. Its main complications in the cardiovascular system include: hypercholesterolaemia, arterial hypertension, left ventricular hypertrophy, early atherosclerotic changes, heart and cerebral infarction. Treatment of obesity is based mainly on changing the patient's lifestyle - diet and physical activity, which can sometimes be problematic and difficult to apply. However, there is a new group of hypoglycaemic drugs - glucagon-like peptide-1 (GLP-1) agonists, which can make obesity treatment easier. These drugs use the incretin effect in the body to increase insulin secretion in response to a meal containing carbohydrates and prevent postprandial hyperglycemia. In this article, we will analyze the latest studies on the effects of GLP-1 receptor agonists, using semaglutide as an example, on the cardiovascular system and on weight loss in patients.
• Object availability:
  free access
• Rights:
  Prawa autorskie (c) 2022 Kamil Pondel, Kinga Kawałko, Krzysztof Bielewicz, Anna Chmura, Anna Karaś;
  http://creativecommons.org/licenses/by-nc-sa/4.0
• Date:
  2022.08.30
• Type:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Language:
  English
• Source:
  Journal of Education, Health and Sport; Vol. 12 No. 9 (2022); 55-60;
  Journal of Education, Health and Sport; Tom 12 Nr 9 (2022); 55-60;
  2391-8306
• Format:
  application/pdf
• Publisher:
  Nicolaus Copernicus University, Toruń, Poland
• Relation: https://apcz.umk.pl/JEHS/article/view/39508/33047
• Subject:
  obesity;
  weight loss;
  GLP-1 agonists;
  cardiovascular risk
• Identifier: https://apcz.umk.pl/JEHS/article/view/39508
• Data provider:
  Akademicka Platforma Czasopism
• Can I use it?:
  seek permission
• Type:
  text