Description

• Title:
  The Long-Term Effects of Alcohol on the Central Nervous System: Mechanisms, Cognitive Decline, and Associated Disorders
• Creator:
  Matuszewska, Marcelina;
  Brzozowska, Monika;
  Wardal, Wiktoria;
  Furlepa, Natalia;
  Rzenno, Robert;
  Wojciechowska, Karolina;
  Wicha, Katarzyna;
  Sidz, Natalia;
  Tomaszewska, Magdalena;
  Jedlikowska, Wiktoria
• Description:
  Prolonged alcohol use exerts significant and multifaceted effects on the central nervous system (CNS). These effects are mediated by mechanisms such as oxidative stress, neuroinflammation, and disruptions in neurotransmission. Structural changes, including gray matter loss and hippocampal atrophy, underlie functional deficits such as memory impairment, cognitive decline, and emotional dysregulation. Chronic alcohol use also increases the risk of neurological conditions, including alcohol-induced dementia, Wernicke-Korsakoff syndrome, and other neurodegenerative diseases. This review synthesizes current findings and highlights the urgent need for longitudinal studies to better understand these impacts and guide intervention strategies.
• Object availability:
  free access
• Rights: https://creativecommons.org/licenses/by-nc-sa/4.0 ;
  Prawa autorskie (c) 2025 Marcelina Matuszewska, Monika Brzozowska, Wiktoria Wardal, Natalia Furlepa, Robert Rzenno, Karolina Wojciechowska, Katarzyna Wicha, Natalia Sidz, Magdalena Tomaszewska, Wiktoria Jedlikowska
• Date:
  2025.04.28
• Type:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Language:
  English
• Source:
  Journal of Education, Health and Sport; Vol. 80 (2025); 59611;
  Journal of Education, Health and Sport; Tom 80 (2025); 59611;
  2391-8306
• Format:
  application/pdf
• Publisher:
  Nicolaus Copernicus University, Toruń, Poland
• Relation: https://apcz.umk.pl/JEHS/article/view/59611/42332
• Subject:
  Alcohol;
  Central Nervous System;
  Neurotoxicity;
  Cognitive Decline;
  Chronic Alcohol Use;
  Neuroinflammation
• Identifier: https://apcz.umk.pl/JEHS/article/view/59611
• Data provider:
  Akademicka Platforma Czasopism
• Can I use it?:
  seek permission
• Type:
  text