Object's details: The role of microRNAs in animal physiology and pathology

Provider:Akademicka Platforma Czasopism

Description

Title:
The role of microRNAs in animal physiology and pathology
Creator:
Szczepanek, Joanna;
Pareek, Chandra S.;
Tretyn, Andrzej
Description:
MicroRNAs are a class of small, evolutionarily conserved, endogenous RNAs, capable of controlling gene expression. MicroRNAs are transcribed by RNA polymerases II and III, generating precursors that undergo a series of cleavage events to form mature microRNA. They play an important regulatory role in animals at the posttranscriptional levels by targeting mRNAs for direct cleavage of mRNAs or repression of mRNA translation. The main biological function of miRNA is the post-translation regulation of cells, like: proliferation and differentiation, cell death, fat metabolism, neuronal patterning and angiogenesis. These molecules are the main regulators of biological features of economic interest, including body growth, muscle development, signaling transduction, fat deposition, and immunology. In this review, we summarize the existing knowledge about miRNAs synthesis, mechanisms for regulation of the genome their functions in animals physiology and the implications associated with dysfunction and dysregulation.
Object availability:
free access
Rights:
Prawa autorskie (c) 2018 Translational Research In Veterinary Science
Date:
2018.12.28
Type:
info:eu-repo/semantics/article;
info:eu-repo/semantics/publishedVersion
Language:
English
Source:
Translational Research in Veterinary Science; Vol. 1 No. 1 (2018); 13-33;
Translational Research In Veterinary Science; Tom 1 Nr 1 (2018); 13-33;
2657-4489
Format:
application/pdf
Publisher:
Nicolaus Copernicus University in Toruń
Relation: https://apcz.umk.pl/TRVS/article/view/TRVS.2018.001/16417
Subject:
miRNA;
biomarkers;
small RNAs;
miRNA based gene regulations
Identifier: https://apcz.umk.pl/TRVS/article/view/TRVS.2018.001
Data provider:
Akademicka Platforma Czasopism

Similar objects

The role of microRNAs in animal physiology and pathology

Creator:Szczepanek, Joanna | Pareek, Chandra S. | Tretyn, Andrzej

Date:2018.12.28

Type:text

MiRNA expression profile in serum of osteoarthritis patients

Date:2019.11.04

Type:text

Rola miRNA w toksyczności nanocząstek srebra

Creator:Paciorek, Patrycja

Date:2023.09.27 | 2023

Type:text

Olaparib Combined with DDR Inhibitors Effectively Prevents EMT and Affects miRNA Regulation in TP53-Mutated Epithelial Ovarian Cancer Cell Lines

Creator:Rogalska, Aneta

Date:2025.02.27 | 2025

Type:text

Potential in anti-cancer therapy using RNA - overview of therapies

Creator:Rusinowska, Barbara

Date:2022.07.28

Type:text

Uncovering miRNA-mRNA Regulatory Networks Related to Olaparib Resistance and Resensitization of BRCA2MUT Ovarian Cancer PEO1-OR Cells with the ATR/CHK1 Pathway Inhibitors, Sonata Bis 2019/34/E/NZ7/00056, Sonata Bis-9 (dataset)

Creator:Rogalska, Aneta

Date:2024.07.02 | 2024

Type:text

Genetic technology in the targeted therapy of Alport Syndrome

Creator:Kłusek, Magdalena | Pawłowski, Bartosz | Sienkiewicz, Michał | Mandziuk, Anna

Date:2025.02.13

Type:text

Konstrukcja i adnotacje sygnatur genowych na bazie eksperymentów porównawczych uzyskiwanych technikami wysokoprzepustowymi w biologii molekularnej

Creator:Łabaj, Wojciech

Date:2019.12.31 | 2019

Type:text

Federacja Bibliotek Cyfrowych

Object's details: The role of microRNAs in animal physiology and pathology

Description

Similar objects