Description

• Title:
  Biological treatment options for severe asthma in Poland
• Creator:
  Superson, Maciej;
  Wilk-Trytko, Klaudia;
  Szmyt, Katarzyna;
  Samojedny, Sylwia;
  Szymańska, Katarzyna;
  Walczak, Kamil;
  Krasnoborska, Julia;
  Zarębska, Julia
• Description:
  Intruduction and purpose: Patients with severe asthma account for approximately 3% to 10% of all asthma patients. They have higher hospital utilization rates and treatment costs than patients with non-severe asthma. Previously, treatment options for these patients were limited due to unacceptable side effects. However, the advent of biologic therapies has provided promising targeted therapy for these patients. State of knowledge: Biologic therapies target inflammatory modulators that play a key role in the pathogenesis of asthma, particularly in patients with high T2 cells. These therapies have shown promising results in reducing asthma symptoms, improving lung function, decreasing the use of oral corticosteroids, and enhancing patients' quality of life. Conclusions: This article reviews the mechanism of action, efficacy, and indications of currently approved biologic drugs available in Poland, as well as potential therapeutic targets for the future.
• Object availability:
  free access
• Rights:
  Prawa autorskie (c) 2024 Maciej Superson, Klaudia Wilk-Trytko, Katarzyna Szmyt, Sylwia Samojedny, Katarzyna Szymańska, Kamil Walczak, Julia Krasnoborska, Julia Zarębska;
  https://creativecommons.org/licenses/by-nc-sa/4.0
• Date:
  2024.05.17
• Type:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Language:
  English
• Source:
  Journal of Education, Health and Sport; Vol. 70 (2024); 51135;
  Journal of Education, Health and Sport; Tom 70 (2024); 51135;
  2391-8306
• Format:
  application/pdf
• Publisher:
  Nicolaus Copernicus University, Toruń, Poland
• Relation: https://apcz.umk.pl/JEHS/article/view/51135/38572
• Subject:
  severe asthma;
  asthma;
  asthma treatments;
  biologics;
  monoclonal antibodies
• Identifier: https://apcz.umk.pl/JEHS/article/view/51135
• Data provider:
  Akademicka Platforma Czasopism
• Can I use it?:
  seek permission
• Type:
  text