Description

• Title:
  Comparison of Antioxidants: The Limited Correlation between Various Assays of Antioxidant Activity
• Creator:
  Soszyński, Mirosław;
  Naparło, Katarzyna;
  Bartosz, Grzegorz;
  Sadowska-Bartosz, Izabela
• Contributor:
  Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 90-236 Lodz, Poland;
  Department of Analytical Biochemistry, Institute of Food Technology and Nutrition, College of Natural Sciences, Rzeszow University, 35-601 Rzeszow, Poland;
  Department of Bioenergetics, Food Analysis and Microbiology, Institute of Food Technology and Nutrition, College of Natural Sciences, Rzeszow University, 35-601 Rzeszow, Poland;
  miroslaw.soszynski@biol.uni.lodz.pl;
  katarzyna.naparlo@gmail.com;
  gbartosz@ur.edu.pl;
  sadowska@ur.edu.pl
• Description:
  The inhibitory effects a range of synthetic and natural antioxidants on lipid peroxidation of egg yolk and erythrocyte membranes induced by a free radical generator 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH) was compared, with significant differences being found between both systems. When the protection by selected antioxidants against the effects of AAPH on erythrocytes (hemolysis, oxidation of hemoglobin and glutathione (GSH) and generation of reactive oxygen species (ROS)) was studied, most antioxidants were protective, but in some tests (oxidation of hemoglobin and GSH) some acted as prooxidants, inducing oxidation in the absence of AAPH and enhancing the AAPH-induced oxidation. These results demonstrate a diversified action of antioxidants in different systems and point to a need for careful extrapolation of any conclusions drawn from one parameter or experimental system to another.;
  This study was performed within the project of the Minister of Science and Higher Education “Regional Initiative of Excellence”, Project No. 026/RID/2018/19.
• Object availability:
  free access
• Rights:
  Uznanie autorstwa 4.0 Międzynarodowe;
  http://creativecommons.org/licenses/by/4.0
• Date:
  2021.10.04;
  2020
• Type:
  Article
• Language:
  English
• Format:
  application/pdf
• Publisher:
  MDPI
• Relation:
  Molecules;25(14);
  3244
• Subject:
  antioxidant;
  lipid peroxidation;
  AAPH;
  hemolysis;
  glutathione;
  reactive oxygen species;
  hemoglobin
• Identifier: http://hdl.handle.net/11089/39320 ;
  1420-3049;
  10.3390/molecules25143244
• Data provider:
  Repozytorium Uniwersytetu Łódzkiego
• Can I use it?:
  check license
• Type:
  image