Description

• Title:
  The emerging role of proactive therapy in atopic dermatitis and psoriasis
• Creator:
  Pięta, Justyna;
  Marcel Chudzikowski;
  Dudek, Patryk;
  Łuczak, Klaudia;
  Pawlik, Agnieszka;
  Prokopiuk, Agata;
  Prus, Joanna;
  Tabeau, Adrianna;
  Ulicka, Wiktoria;
  Sitarek, Hanna
• Description:
  Proactive therapy represents an evolving approach in the long-term management of atopic dermatitis (AD) and psoriasis. Unlike reactive treatment, which targets active symptoms, proactive therapy involves the intermittent, low-dose application of anti-inflammatory agents to previously affected but clinically healed skin to prevent flare-ups. This strategy aims to reduce subclinical inflammation, extend remission periods, and improve patient quality of life. A growing body of evidence supports the efficacy of proactive treatment with topical corticosteroids, calcineurin inhibitors, and vitamin D analogues, demonstrating significant reductions in relapse rates and treatment costs. However, patient adherence remains a key challenge, necessitating structured follow-up and patient education initiatives. This review explores the pathophysiological basis of proactive therapy, its clinical applications, and current evidence supporting its role in AD and psoriasis management. Additionally, we discuss safety concerns, particularly regarding skin atrophy and hypothalamic-pituitary-adrenal axis suppression, and highlight emerging therapeutic options. While proactive therapy has demonstrated a favourable benefit-risk profile, further studies are needed to refine treatment protocols and expand its application to broader patient populations.
• Object availability:
  free access
• Rights: https://creativecommons.org/licenses/by-nc-sa/4.0 ;
  Prawa autorskie (c) 2025 Justyna Pięta, Marcel Chudzikowski, Patryk Dudek, Klaudia Łuczak, Agnieszka Pawlik, Agata Prokopiuk, Joanna Prus, Adrianna Tabeau, Wiktoria Ulicka, Hanna Sitarek
• Date:
  2025.04.28
• Type:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Language:
  English
• Source:
  Journal of Education, Health and Sport; Vol. 80 (2025); 59456;
  Journal of Education, Health and Sport; Tom 80 (2025); 59456;
  2391-8306
• Format:
  application/pdf
• Publisher:
  Nicolaus Copernicus University, Toruń, Poland
• Relation: https://apcz.umk.pl/JEHS/article/view/59456/42310
• Subject:
  proactive therapy;
  maintenance therapy;
  topical treatment;
  atopic dermatitis;
  psoriasis
• Identifier: https://apcz.umk.pl/JEHS/article/view/59456
• Data provider:
  Akademicka Platforma Czasopism
• Can I use it?:
  seek permission
• Type:
  text