Object's details: Characteristic of warfarin

Provider:Akademicka Platforma Czasopism

Description

Title:
Characteristic of warfarin
Creator:
Baran, Marzena Teresa;
Miziak, Paulina;
Bonio, Katarzyna
Description:
In modern pharmacology, compounds of natural origin are gaining more and more recognition. One of them is warfarin, which is a compound of organic coumarin derivatives. It is used medicinally in the anticoagulant doctor. This compound was commercially introduced to the United States in the 1950s. It has been available on the Polish market since 2006. Warfarin is an antagonist of vitamin K. It works by inhibiting the synthesis of vitamin K in the liver and thus blocking the synthesis of vitamin K dependent blood clotting factors (II, VII, IX, X). It is widely used by people suffering from cardiovascular diseases such as venous thrombosis and venous embolism. Adopted by patients with suspected or after a heart attack. Despite its undisputed positive effect, one should remember about the numerous side effects resulting from long-term use of warfarin. They may be due to intolerance to this compound, which causes nausea, vomiting, and allergic reactions. Moreover, recent studies show that it may have a destructive effect on the liver and cause calcification of blood vessels. Keep in mind that warfarin can interact with many substances you are taking for other medical conditions. Agents that increase the effects of warfarin include antibiotics such as erythromycin, deoxicillin, commonly used drugs containing caffeine, acetylsalicylic acid and naturally derived compounds found in ginkgo, garlic and sage. Compounds that weaken the effect of warfarin are barbiturates, cyclosporine, vitamin C, and St. John's wort.
Object availability:
free access
Rights:
Prawa autorskie (c) 2020 © The Author(s)
Date:
2020.08.01
Type:
info:eu-repo/semantics/article;
info:eu-repo/semantics/publishedVersion
Language:
English
Source:
Journal of Education, Health and Sport; Vol. 10 No. 8 (2020); 78-80;
Journal of Education, Health and Sport; Tom 10 Nr 8 (2020); 78-80;
2391-8306
Format:
application/pdf
Publisher:
Nicolaus Copernicus University, Toruń, Poland
Relation: https://apcz.umk.pl/JEHS/article/view/JEHS.2020.10.08.009/26225
Subject:
warfarin;
cumarine;
vitamin K antagonist;
medicine;
anticoagulants
Identifier: https://apcz.umk.pl/JEHS/article/view/JEHS.2020.10.08.009
Data provider:
Akademicka Platforma Czasopism

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Object's details: Characteristic of warfarin

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