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Streptozotocin - an antibiotic used to induce diabetes on experimental animals

Object's details: Streptozotocin - an antibiotic used to induce diabetes on experimental animals

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Provider:Akademicka Platforma Czasopism

Description

Title:
Streptozotocin - an antibiotic used to induce diabetes on experimental animals
Creator:
Siedlecka, Dagna;
Micał, Wojciech;
Krzewicka-Romaniuk, Ewa
Description:
Streptozotocin (STZ) is a cytostatic antibiotic produced by Streptomyces achromogenes. It is an inhibitor of DNA replication showing a special affinity for pancreatic β-cells DNA. It is used in medicine as an antineoplastic agent (indicated in the treatment of malignant neoplasms of pancreas) and in scientific research to induce hyperglycemia, insulitis, diabetes mellitus (DM), Alzheimer’s disease on experimental animals. Insulinopenia syndrome is called ‘streptozotocin diabetes’, caused by necrosis of the pancreatic β-cells. STZ induced DM offers a very cost-effective and expeditious technique in medical research.
Object availability:
free access
Rights:
Prawa autorskie (c) 2020 © The Author(s)
Date:
2020.09.30
Type:
info:eu-repo/semantics/article;
info:eu-repo/semantics/publishedVersion
Language:
English
Source:
Journal of Education, Health and Sport; Vol. 10 No. 9 (2020); 906-909;
Journal of Education, Health and Sport; Tom 10 Nr 9 (2020); 906-909;
2391-8306
Format:
application/pdf
Publisher:
Nicolaus Copernicus University, Toruń, Poland
Relation: https://apcz.umk.pl/JEHS/article/view/JEHS.2020.10.09.110/26702
Subject:
STZ;
streptozotocin;
streptozocin;
streptozotocin diabetes
Identifier: https://apcz.umk.pl/JEHS/article/view/JEHS.2020.10.09.110
Data provider:
Akademicka Platforma Czasopism

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