Description

• Title:
  GLP-1 Receptor Agonists’ Impact on Fertility - A Review
• Creator:
  Wojda, Joanna;
  Lesiczka-Fedoryj, Katarzyna;
  Walczak, Anna;
  Kościuszko, Zuzanna;
  Sobiński, Adam;
  Czerwonka, Matylda;
  Kurza, Katarzyna;
  Podolec, Julianna;
  Ciraolo, Silvia;
  Agnieszka Kulczycka-Rowicka
• Description:
  Purpose of Research: The aim of the research is to summarize the impact of GLP-1 analogs on fertility according to clinical studies, particularly in obese or overweight women with PCOS.  Research Materials and Methods: The study is built upon an analysis of current literature, clinical trials, meta-analyses, and systematic reviews as well as press reports from various sources. Data were collected from studies examining the effects of obesity on fertility, as well as the impact of GLP-1 analogs on both fertility and obesity. Basic Results: GLP-1 analogs promote weight management among obese and overweight patients leading to improvement in their fertility. Furthermore, they improve pregnancy rates in women with PCOS, although further examination is needed. Conclusions: We observe, GLP-1 analogs are often used in regulation of type 2 diabetes. They have proven their ability to impact a variety of hormonal as well as metabolic pathways. They manage glucose metabolism, appetite, as well as insulin secretion. Alongside their metabolic influence, research demonstrates that GLP-1 analogs may have an effect on the reproductive system, involving fertility via metabolic and hormonal pathways.    
• Object availability:
  free access
• Rights:
  Prawa autorskie (c) 2025 Joanna Wojda, Katarzyna Lesiczka-Fedoryj, Anna Walczak, Zuzanna Kościuszko, Adam Sobiński, Matylda Czerwonka, Katarzyna Kurza, Julianna Podolec, Silvia Ciraolo, Agnieszka Kulczycka-Rowicka;
  https://creativecommons.org/licenses/by-nc-sa/4.0
• Date:
  2025.02.11
• Type:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Language:
  English
• Source:
  Quality in Sport; Tom 38 (2025); 58325;
  Quality in Sport; Vol. 38 (2025); 58325;
  2450-3118
• Format:
  application/pdf
• Publisher:
  University Center for Sports Research, Nicolaus Copernicus University, Torun, Poland
• Relation: https://apcz.umk.pl/QS/article/view/58325/41509
• Subject:
  GLP-1 analog;
  fertility;
  obesity;
  PCOS
• Identifier: https://apcz.umk.pl/QS/article/view/58325
• Data provider:
  Akademicka Platforma Czasopism
• Can I use it?:
  seek permission
• Type:
  text