Description

• Title:
  Relationships between geomagnetic Ар-indeх and parameters of the immunity in patients with multiple sclerosis and radiculopathies
• Creator:
  Popovych, Igor;
  Gozhenko, Anatoliy;
  Badiuk, Nataliya;
  Napierała, Marek;
  Muszkieta, Radosław;
  Zukow, Walery;
  Yanchij, Roman;
  Lapovets’, Natalia;
  Lapovets’, Lyubov;
  Tserkovnyuk, Ruslan;
  Akimova, Viorica;
  Nahurna, Yaryna;
  Martianova, Olha;
  Vivchar, Roman;
  Chendey, Ivanna;
  Ruzhylo, Sofiya
• Description:
  Background. The effect of geomagnetism on human immunity has so far been studied through long-term observations. We set ourselves the goal of detecting the immediate immunotropic effects of the Earth's magnetic field by analyzing the relationships between immunity parameters and the geomagnetic Ap-index. Material and methods. The object of observation were 74 patients with multiple sclerosis and 14 patients with radiculopathies, who in the period from September 2014 to November 2018 conducted a one-time assessment of immune status by the relative content in the blood of lymphocytes of CD3+, CD4+, CD8+, CD25+, CD56+ and CD19+ phenotypes and serum level of Immunoglobulines M, G, A as well as CIC and IL-1β. On the day of blood capture and during the previous 7 days, retrospectively recorded the geomagnetic Ap-index, using a publicly available information resource http://wdc.kugi.kyoto-u.ac.jp/kp/index.html. Results. During the week, the average level of Ap-index ranged from 12÷20 nT. The correlation coefficients between the Ap-index on the day of blood collection and 1, 3 and 7 days before it and the level of CD3+CD4+ lymphocytes were -0,57; -0,48; -0,55 і -0,52 respectively, while on other days were in the range of -0,35÷0,05. In contrast, with the level of CD56+ lymphocytes Ap-index correlates positively and almost mirror (0,56; 0,43; 0,54 і 0,57 respectively and 0,34÷-0,08), due to the reciprocity of their levels (r=-0,80). Also positive, but much weaker, correlates the Ap-index with the level of CD25+ lymphocytes (0,35; 0,25; 0,45 і 0,31 respectively and 0,22÷-0,14). In contrast, with the level of IL-1β Ap-index correlates significantly only on the day of blood collection and 2 days before (r=0,21 and 0,31 respectively), and with other registered parameters of immunity the correlation is insignificant. The canonical correlation between Ap-indices for 7 days before and on the day of blood collection, on the one hand, and the levels of CD4+, CD56+, CD25+ and CD8+ lymphocytes and the concentration of IgM and IL-1β - on the other hand, was very strong: R=0,741; R2=0,549; χ2(42)=130; p<10-6. Conclusion. Disturbances of the geomagnetic field (Ap-index) has a significant immediate modulating effect on the level of immune parameters in the blood, mostly T-helpers (suppressor) and natural killers (enhancing).
• Object availability:
  free access
• Rights: http://creativecommons.org/licenses/by-nc-sa/4.0 ;
  Prawa autorskie (c) 2021 © The Author(s)
• Date:
  2021.03.25
• Type:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Language:
  English
• Source:
  Journal of Education, Health and Sport; Vol. 11 No. 3 (2021); 77-90;
  Journal of Education, Health and Sport; Tom 11 Nr 3 (2021); 77-90;
  2391-8306
• Format:
  application/pdf
• Publisher:
  Nicolaus Copernicus University, Toruń, Poland
• Relation: https://apcz.umk.pl/JEHS/article/view/JEHS.2021.11.03.009/28565
• Subject:
  geomagnetic Ap-index;
  immune status;
  multiple sclerosis;
  radiculopathy.
• Identifier: https://apcz.umk.pl/JEHS/article/view/JEHS.2021.11.03.009
• Data provider:
  Akademicka Platforma Czasopism
• Can I use it?:
  seek permission
• Type:
  text