Description

• Title:
  A Comprehensive Review of Sarcoidosis: From Clinical Manifestations to Management Strategies
• Creator:
  Śpiołek, Olga;
  Siwiec, Jan;
  Słowikowska, Aleksandra;
  Teofilak, Mateusz;
  Szatkowska, Julia;
  Smyl, Natalia;
  Sztyler-Krąkowska, Marcelina;
  Wąsowicz, Agnieszka;
  Kędziora, Franciszek;
  Fabian, Dariusz
• Description:
  Introduction and purpose: Sarcoidosis is a complex, multi – system disease characterized by the formation of non – caseating granulomas that can affect nearly every organ in the body, though lungs and lymph nodes are the most commonly involved. The disease's clinical presentation is highly variable, ranging from asymptomatic cases to severe, organ-threatening manifestations, with significant implications for diagnosis and treatment.  The aim of this study is to present current state of knowledge on clinical features, etiology, diagnosis and treatment methods of sarcoidosis.  Materials and methods: The review is based on the analysis of literature available on Pubmed, Google Scholar and UpToDate databases. To search for relevant scientific content the following keywords were used: sarcoidosis, symptoms, etiology, diagnosis, treatment, neurosarcoidosis, cutaneous sarcoidosis, cardiac sarcoidosis, Löfgren syndrome. Conclusions: Despite numerous studies, the cause of sarcoidosis still remains unknown, which leaves a field for researchers for further investigation. Diagnosis of sarcoidosis is challenging, it typically involves histological confirmation through biopsy, supported by imaging studies, laboratory tests and need to exclude other causes. Treatment is limited, focused on alleviating the symptoms and preventing organ failure, therefore further research into more effective or targeted therapies is advisable. 
• Object availability:
  free access
• Rights: https://creativecommons.org/licenses/by-nc-sa/4.0 ;
  Prawa autorskie (c) 2024 Olga Śpiołek, Jan Siwiec, Aleksandra Słowikowska, Mateusz Teofilak, Julia Szatkowska, Natalia Smyl, Marcelina Sztyler-Krąkowska, Agnieszka Wąsowicz, Franciszek Kędziora, Dariusz Fabian
• Date:
  2024.12.20
• Type:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Language:
  English
• Source:
  Journal of Education, Health and Sport; Vol. 75 (2024); 56452;
  Journal of Education, Health and Sport; Tom 75 (2024); 56452;
  2391-8306
• Format:
  application/pdf
• Publisher:
  Nicolaus Copernicus University, Toruń, Poland
• Relation: https://apcz.umk.pl/JEHS/article/view/56452/40798
• Subject:
  sarcoidosis;
  neurosarcoidosis;
  pulmonary fibrosis;
  cardiac sarcoidosis;
  Löfgren syndrome
• Identifier: https://apcz.umk.pl/JEHS/article/view/56452
• Data provider:
  Akademicka Platforma Czasopism
• Can I use it?:
  seek permission
• Type:
  text