Description

• Title:
  The impact of L-Arginine supplementation on disorders associated with obesity
• Creator:
  Justyna Żyga
• Description:
  Introduction: L-Arginine (2-amino-5-guanidinovaleric acid) is a conditionally essential amino acid and a natural constituent of dietary proteins, serving as a precursor for the synthesis not only of proteins, urea, polyamines, proline, glutamate and creatine. This amino acid is a substrate for nitric oxide production, an endogenous messenger molecule involved in a variety of endothelium mediated physiological effects in the vascular system.  State of knowledge: The evidence suggests supplementation of L-Arginine may have a positive impact in conditions associated with obesity - type 2 diabetes, atherosclerosis or hypercholesterolaemia. The L-Arginine intake improves insulin sensitivity and may improve lipid profile reducing triglyceride serum levels. As a precursor for nitric oxide synthesis, a molecule involved in a variety of physiological effects in the vascular system, L-Arginine can have a positive impact on the cardiovascular system. Conclusions: The evidence suggests that the L-Arginine may improve lipid profile reducing triglyceride serum levels. L-Arginine could be used as a strategy to improve endothelial function in the selected group of patients. Careful studies are necessary to assess its safety profile, determine under which conditions L-Arginine supplementation is appropriate and when it is undesirable. Attention should be focused to markers of oxidative stress and blood pressure stability.
• Object availability:
  free access
• Rights:
  Prawa autorskie (c) 2022 Justyna Żyga;
  http://creativecommons.org/licenses/by-nc-sa/4.0
• Date:
  2022.08.31
• Type:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Language:
  English
• Source:
  Journal of Education, Health and Sport; Vol. 12 No. 9 (2022); 223-228;
  Journal of Education, Health and Sport; Tom 12 Nr 9 (2022); 223-228;
  2391-8306
• Format:
  application/pdf
• Publisher:
  Nicolaus Copernicus University, Toruń, Poland
• Relation: https://apcz.umk.pl/JEHS/article/view/39456/33074
• Subject:
  L-arginine;
  cardiovascular disease;
  metabolic disorder;
  insulin resistance;
  obesity
• Identifier: https://apcz.umk.pl/JEHS/article/view/39456
• Data provider:
  Akademicka Platforma Czasopism
• Can I use it?:
  seek permission
• Type:
  text