Object's details: Specificity of blood pressure numbers in Holter monitoring depending on gene polymorphism among residents of Ternopil region afflicted with essential arterial hypertension

Provider:Akademicka Platforma Czasopism

Description

Title:
Specificity of blood pressure numbers in Holter monitoring depending on gene polymorphism among residents of Ternopil region afflicted with essential arterial hypertension
Creator:
Hnizdyukh, Roman Volodymyrovych;
Shmanko, Volodymyr Vasylovych
Description:
The aim of this work is to determine specificities of blood pressure (BP) numbers during the day depending on polymorphism of the A1166C-gene of angiotensin II receptor type I and T786C-promoter of the endothelial NO-synthase gene among residents of Ternopil region afflicted with essential arterial hypertension.We have examined 86 patients with arterial hypertension who were treated and examined in the therapeutic department of the Central District Hospital in Kozova, aged from 45 to 76 years. All patients were measured for body weight and height, office blood pressure; also they were checked by Holter monitoring and electrocardiography (ECG), as well as examined for polymorphism of endothelial NO synthase genes and angiotensin II type 1 receptor genes. Statistical processing of the obtained data was performed with the help of the analytics software package including Statistica 8.0 (StatSoft Inc., USA) and Microsoft Office Excel-2003.The research revealed that patients with CC genotype A1166C-gene of angiotensin II receptor of the first type had a significantly higher level of systolic blood pressure (SBP) and diastolic blood pressure (DBP) – average numbers per 24 hours, day and night – compared to patients with genotype AA(p<0,05). Hereby, no significant distinctions in blood pressure variability were found.Patients with CC of the T786C promoter of the eNOs gene had higher SBP and DBP values at all times of the day compared to individuals with the TT genotype (p <0.05). Increased levels of variability of DBP during the day, as well as SBP and DBP at night, were observed among patients with CC genotype, as compared with the control group (p <0.05).Among patients with C-allele of both studied genes, there’s a high frequency of circadian rhythm disorders with predominance of the “non-dippers” pathological type.
Object availability:
free access
Rights:
Prawa autorskie (c) 2021 © The Author(s)
Date:
2021.07.20
Type:
info:eu-repo/semantics/article;
info:eu-repo/semantics/publishedVersion
Language:
English
Source:
Journal of Education, Health and Sport; Vol. 11 No. 7 (2021); 124-134;
Journal of Education, Health and Sport; Tom 11 Nr 7 (2021); 124-134;
2391-8306
Format:
application/pdf
Publisher:
Nicolaus Copernicus University, Toruń, Poland
Relation: https://apcz.umk.pl/JEHS/article/view/JEHS.2021.11.07.011/29361
Subject:
arterial hypertension;
gene polymorphism;
Holter blood pressure monitoring.
Identifier: https://apcz.umk.pl/JEHS/article/view/JEHS.2021.11.07.011
Data provider:
Akademicka Platforma Czasopism

Similar objects

Specificity of blood pressure numbers in Holter monitoring depending on gene polymorphism among residents of Ternopil region afflicted with essential arterial hypertension

Creator:Hnizdyukh, Roman Volodymyrovych | Shmanko, Volodymyr Vasylovych

Date:2021.07.20

Type:text

Morphometric analysis of structural arrangement of the testial arteries in postresectional arterial pulmonary hypertension

Creator:Konovalenko, S. O.

Date:2020.02.28

Type:text

Effect of hypertension on uric acid metabolism in patients with gout

Date:2023.02.18

Type:text

Relationship between metabolic syndrome components in patients with resistant arterial hypertension

Creator:Shmakova, I. P. | Panina, S. A. | Shishova, P. A.

Date:2021.06.30

Type:text

Clinical and psychopathological features of the course and outcome of the first psychotic episode.

Creator:Bazhora, Yuri | Gudz, Valentyn | Mozgova, Valentina | Usychenko, Kateryna | Shvets, Nikol

Date:2023.11.30

Type:text

The Use of Benzodiazepines in the Management of Hypertensive Crisis: A Literature Review

Date:2025.01.10

Type:text

Assessment of the state of intracardiac hemodynamics and myocardial remodeling in women with gonarthritis, hypertension and overweight

Creator:Pidlubna, A.

Date:2021.07.29

Type:text

Features of hyperplastic processes of the endometrium in the presence of arterial hypertension

Creator:Zemlianiy, Yaroslav | Zemlyana, Natalie

Date:2023.08.06

Type:text

Federacja Bibliotek Cyfrowych

Object's details: Specificity of blood pressure numbers in Holter monitoring depending on gene polymorphism among residents of Ternopil region afflicted with essential arterial hypertension

Description

Similar objects