Object's details: The impact of Bacillus Calmette-Guérin (BCG) vaccination on the course of COVID-19: effectiveness and possible mechanism

Provider:Akademicka Platforma Czasopism

Description

Title:
The impact of Bacillus Calmette-Guérin (BCG) vaccination on the course of COVID-19: effectiveness and possible mechanism
Creator:
Gałązka, Jakub Krzysztof
Description:
Nowadays, Bacillus Calmette-Guérin (BCG) is the most commonly used vaccine worldwide, used typically for tuberculosis but also in non-muscle invasive bladder cancer management. Basing on previously confirmed antiviral features of BCG and first statistic data reports, BCG usage in COVID-19 prevention was claimed and its potential molecular mechanism was searched. In scientific literature there was 10 publications proving several possible mechanism of BCG interaction with SARS-CoV-2 infection immune response. The most often was cross-reactivity between various BCG and SARS-CoV-2 antigens, including those crucial for their clinical effects. In most cases, those antigens linking was shown according to bioinformatical research. According to this research, the potential role of BCG in COVID-19 management should be considered as significant, at least until the clinical trials conducted nowadays will be over.
Object availability:
free access
Rights: https://creativecommons.org/licenses/by-nc-sa/4.0 ;
Prawa autorskie (c) 2022 Jakub Krzysztof Gałązka
Date:
2022.10.08
Type:
info:eu-repo/semantics/article;
info:eu-repo/semantics/publishedVersion
Language:
English
Source:
Journal of Education, Health and Sport; Vol. 12 No. 10 (2022); 132-142;
Journal of Education, Health and Sport; Tom 12 Nr 10 (2022); 132-142;
2391-8306
Format:
application/pdf
Publisher:
Nicolaus Copernicus University, Toruń, Poland
Relation: https://apcz.umk.pl/JEHS/article/view/40380/33385
Subject:
BCG;
Bacillus Calmette-Guérin;
vaccine;
COVID-19
Identifier: https://apcz.umk.pl/JEHS/article/view/40380
Data provider:
Akademicka Platforma Czasopism

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Object's details: The impact of Bacillus Calmette-Guérin (BCG) vaccination on the course of COVID-19: effectiveness and possible mechanism

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