Description

• Title:
  Understanding cannabinoid receptors: structure and function
• Creator:
  Andrzejewska, Angelika;
  Staszak, Klaudia;
  Kaczmarek-Ryś, Marta;
  Słomski, Ryszard;
  Hryhorowicz, Szymon
• Contributor:
  Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, 60-479 Poznan, Poland;
  Department of Biochemistry and Biotechnology, University of Life Sciences, Dojazd 11, 60-632 Poznan, Poland;
  szymon.hryhorowicz@igcz.poznan.pl
• Description:
  The endocannabinoid system (ECS) consists of the endocannabinoids, cannabinoid receptors and the enzymes that synthesize and degrade endocannabinoids. The whole EC system plays an important role in the proper functioning of the central and autonomic nervous system. ECS is involved in the regulation of the body energy and in the functioning of the endocrine system. It can affect on the regulation of emotional states, motoric movement, operations of the endocrine, immune and digestive system. Many of the effects of cannabinoids are mediated by G coupled –protein receptors: CB1, CB2 and GPR55 but also of transient receptor potential channels (TRPs) which not only induce the sensation of pain but also support inflammation via secretion of pro-inflammatory neuropeptides. In this review work we briefly summarize the role and action of cannabinoid receptors CB1 and CB2, protein-coupled receptor 55 (GPR55) and transient receptor potential vanilloid 1 (TRPV1).
• Object availability:
  free access
• Rights:
  This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.;
  http://creativecommons.org/licenses/by-nc-nd/3.0
• Date:
  2019.12.03;
  2019.02.01
• Format:
  application/pdf
• Publisher:
  Lodz University Press
• Relation:
  Folia Biologica et Oecologica;14
• Subject:
  cannabinoid receptors;
  CB1;
  CB2;
  TRPV1;
  GPR55
• Identifier:
  1730-2366;
  http://hdl.handle.net/11089/30987 ;
  2083-8484;
  10.1515/fobio-2017-0004
• Data provider:
  Repozytorium Uniwersytetu Łódzkiego
• Can I use it?:
  check license
• Type:
  other