Object's details: Pharmacotherapy for Alcohol Use Disorder: Enhancing Health and Treatment Outcomes

Provider:Akademicka Platforma Czasopism

Description

Title:
Pharmacotherapy for Alcohol Use Disorder: Enhancing Health and Treatment Outcomes
Creator:
Moczyróg, Katarzyna;
Sierpińska, Aleksandra;
Jaksz, Agata;
Jasiewicz, Maria;
Karnas-Bogacka, Patrycja;
Malicka, Marta;
Kozioł, Aleksandra;
Mól, Piotr
Description:
Introduction and Objective: Alcohol Use Disorder (AUD) combines alcohol abuse and dependence into a single condition characterized by an inability to control alcohol consumption despite its negative consequences. Treatment for AUD includes both pharmacological and behavioral therapies aimed at achieving complete abstinence. This paper reviews pharmacological treatment options and their clinical effectiveness. Given the increasing prevalence of AUD globally, including in Poland, understanding the availability, efficacy, and cost of these treatments is essential to improve patient outcomes.  Review methods: This review analyzes current literature on pharmacological treatments for AUD, including medications approved by FDA and EMA. Sources include peer-reviewed articles and clinical trials. Results: Naltrexone and nalmefene have been shown to be effective in reducing alcohol consumption and cravings, while acamprosate and topiramate are particularly effective in relapse prevention and maintaining abstinence. Gabapentin is effective in treating alcohol withdrawal symptoms, while baclofen, mifepristone, and N-acetylcysteine show promising results but require further research. Ondansetron has been documented as effective in treating young patients with early-onset AUD, and varenicline effectively reduces alcohol cravings in individuals with nicotine dependence. The disulfiram implant is ineffective in treating alcohol dependence and maintaining abstinence, with its action primarily based on the fear of a disulfiram reaction. Conclusions: Pharmacological treatments for AUD, combined with behavioral therapy, help reduce alcohol consumption or maintain abstinence. Individualized therapy selection is crucial, taking into account the patient's health status and the presence of other conditions. Further research is required to optimize treatment, both in terms of pharmacological mechanisms and better tailoring the therapy to the specific needs of individual patients.
Object availability:
free access
Rights: https://creativecommons.org/licenses/by-nc-sa/4.0 ;
Prawa autorskie (c) 2025 Katarzyna Moczyróg, Aleksandra Sierpińska, Agata Jaksz, Maria Jasiewicz, Patrycja Karnas-Bogacka, Marta Malicka, Aleksandra Kozioł, Piotr Mól
Date:
2025.03.05
Type:
info:eu-repo/semantics/article;
info:eu-repo/semantics/publishedVersion
Language:
English
Source:
Quality in Sport; Tom 39 (2025); 58999;
Quality in Sport; Vol. 39 (2025); 58999;
2450-3118
Format:
application/pdf
Publisher:
University Center for Sports Research, Nicolaus Copernicus University, Torun, Poland
Relation: https://apcz.umk.pl/QS/article/view/58999/41699
Subject:
naltrexone;
nalmefene;
acamprosate;
disulfiram;
gabapentin;
topiramate;
baclofen;
N-acetylcysteine;
mifepristone;
ondansetron;
varenicline
Identifier: https://apcz.umk.pl/QS/article/view/58999
Data provider:
Akademicka Platforma Czasopism

Similar objects

Pharmacotherapy for Alcohol Use Disorder: Enhancing Health and Treatment Outcomes

Date:2025.03.05

Type:text

Evaluation of the effectiveness and safety of anti-obesity drugs - an update on the current state of knowledge on available and investigational drugs

Date:2023.05.31

Type:text

N-Acetycysteine effects on microsomal monooxygenase system and glutathione levelsin rats after paracetamol and/or trichloroethylene singleoral intoxication

Date:2003

Type:other

Alternative use of the cough drug - N-acetylcysteine in psychiatry: a review of recent clinical trials

Creator:Cieszkowska, Joanna | Czubala, Marta | Czerwik, Julia | Dmochowska, Joanna

Date:2024.05.13

Type:text

Expanding Horizons – A Broad-Spectrum Review of Emerging Medical Applications of N-Acetylcysteine

Date:2025.07.09

Type:text

The impact of omega-3 fatty acids, vitamins, minerals, N-acetylcysteine, and ginkgo biloba on the course and treatment of schizophrenia: A review of research and therapeutic perspectives

Date:2025.05.12

Type:text

Baclofen - a great chance or danger - discussion of poisoning based on research

Date:2023.08.24

Type:text

The Review of pharmacological treatment registered for obesity in Poland

Date:2024.02.01

Type:text

Federacja Bibliotek Cyfrowych

Object's details: Pharmacotherapy for Alcohol Use Disorder: Enhancing Health and Treatment Outcomes

Description

Similar objects