Description

• Title:
  Evaluating the Role and Efficacy of Cobenfy (Xanomeline and Trospium Chloride) in Schizophrenia Treatment - review
• Creator:
  Mazur, Michał;
  Żak , Katarzyna;
  Michalak , Katarzyna;
  Zukierski , Krystian;
  Jarych, Weronika;
  Pliszka , Aleksandra;
  Jucha , Hubert;
  Madyniak , Katarzyna;
  Kluz , Agnieszka
• Description:
  Schizophrenia is a complex psychiatric disorder often resistant to dopamine-targeting antipsychotics. Cobenfy, a combination of xanomeline and trospium chloride, offers a novel approach by modulating muscarinic receptors while minimizing side effects. This review evaluates its efficacy and safety, particularly in treatment-resistant cases. Clinical trials show significant reductions in both positive and negative symptoms, positioning Cobenfy as a promising alternative.
• Object availability:
  free access
• Rights: https://creativecommons.org/licenses/by-nc-sa/4.0 ;
  Prawa autorskie (c) 2025 Michał Mazur, Katarzyna Żak , Katarzyna Michalak , Krystian Zukierski , Weronika Jarych, Aleksandra Pliszka , Hubert Jucha , Katarzyna Madyniak , Agnieszka Kluz
• Date:
  2025.04.23
• Type:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Language:
  English
• Source:
  Quality in Sport; Tom 40 (2025); 59815;
  Quality in Sport; Vol. 40 (2025); 59815;
  2450-3118
• Format:
  application/pdf
• Publisher:
  University Center for Sports Research, Nicolaus Copernicus University, Torun, Poland
• Relation: https://apcz.umk.pl/QS/article/view/59815/42288
• Subject:
  Cobenfy;
  xanomeline-trospium;
  muscarinic receptor modulation;
  schizophrenia treatment;
  non-dopaminergic antipsychotics;
  EMERGENT trials;
  antipsychotic therapy.
• Identifier: https://apcz.umk.pl/QS/article/view/59815
• Data provider:
  Akademicka Platforma Czasopism
• Can I use it?:
  seek permission
• Type:
  text