Description

• Title:
  Exploring the Therapeutic Potential of Sodium Butyrate in Irritable Bowel Syndrome. A Literature Review
• Creator:
  Miga, Nadia;
  Lemieszek, Paulina;
  Sajkiewicz, Ilona;
  Rudnicka, Katarzyna
• Description:
  Introduction and purpose Irritable bowel syndrome (IBS) is a prevalent digestive condition marked by symptoms like abdominal discomfort, bloating, and irregular bowel movements. Sodium butyrate, a short-chain fatty acid recognized for its anti-inflammatory effects and benefits to gut health, has gained attention as a potential treatment for IBS. This review seeks to assess the existing research on the effectiveness and safety of sodium butyrate in managing IBS. Material and methods This work was based on a review of the literature available on PubMed. We included studies corresponding to the keywords: sodium butyrate, irritable bowel disease, butyric acid. Results Research has shown that sodium butyrate supplementation significantly alleviated abdominal pain, bloating, and overall IBS symptoms compared to a placebo. Notable improvements were seen in both visceral pain sensitivity and gut permeability. Furthermore, combining sodium butyrate with probiotics may offer additional benefits. The treatment was generally well-tolerated, easily accessible, and cost-effective. Conclusion Sodium butyrate shows promise as a therapeutic option for managing IBS, with studies indicating its effectiveness in reducing symptoms and enhancing gut health. However, more extensive, well-structured clinical trials are required to validate these results, determine optimal dosage, and assess long-term safety and efficacy.
• Object availability:
  free access
• Rights:
  Prawa autorskie (c) 2024 Nadia Miga-Orczykowska, Paulina Lemieszek, Ilona Sajkiewicz, Katarzyna Rudnicka;
  https://creativecommons.org/licenses/by-nc-sa/4.0
• Date:
  2024.09.24
• Type:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Language:
  English
• Source:
  Journal of Education, Health and Sport; Vol. 68 (2024); 55326;
  Journal of Education, Health and Sport; Tom 68 (2024); 55326;
  2391-8306
• Format:
  application/pdf
• Publisher:
  Nicolaus Copernicus University, Toruń, Poland
• Relation: https://apcz.umk.pl/JEHS/article/view/55326/39828
• Subject:
  sodium butyrate;
  irritable bowel syndrome;
  butyric acid;
  SCFAs
• Identifier: https://apcz.umk.pl/JEHS/article/view/55326
• Data provider:
  Akademicka Platforma Czasopism
• Can I use it?:
  seek permission
• Type:
  text