Description

• Title:
  What are the newest outcomes about Legg-Calve-Perthes disease etiology after 110 years over its discovering ? – literature review
• Creator:
  Węgrzyniak, Agata;
  Wokurka, Wojciech;
  Dudek, Iga;
  Piech, Piotr
• Description:
  Idiopathic avascular necrosis of the femoral head, known as Legg-Calve-Perthes disease (LCPD), is one of the most common necrosis among paediatric patients. Although it was described over 110 years ago its aetiology is still not established. Neither have effective treatment methods, which main aim is to maintain the joint with a full range of motion and to reduce the risk of developing degenerative changes. According to the literature, the exact aetiology of LCPD has still not been established. Increasingly, immunological and genetic disorders are highlighted in the literature, which may be an important cause of disease development. However, the number of reliable studies on this subject is very limited. Once again, the influence of various risk factors present in fetal life has been analysed, but in a study with a significantly larger group of subjects. It has been repeatedly stressed that age, stage and radiological classification have a very important influence on the choice of treatment method and its effectiveness. Another important aspect is the need for reliable clinical trials to determine the effectiveness of bisphosphonate drugs and BMPs (bone morphogenetic proteins). In all studies, the need to perform more studies, on quantitatively larger groups of subjects, is significantly emphasized.
• Object availability:
  free access
• Rights: http://creativecommons.org/licenses/by-nc-sa/4.0 ;
  Prawa autorskie (c) 2021 Agata Węgrzyniak, Wojciech Wokurka, Iga Dudek, Piotr Piech
• Date:
  2021.09.21
• Type:
  info:eu-repo/semantics/article;
  info:eu-repo/semantics/publishedVersion
• Language:
  English
• Source:
  Journal of Education, Health and Sport; Vol. 11 No. 9 (2021); 396-400;
  Journal of Education, Health and Sport; Tom 11 Nr 9 (2021); 396-400;
  2391-8306
• Format:
  application/pdf
• Publisher:
  Nicolaus Copernicus University, Toruń, Poland
• Relation: https://apcz.umk.pl/JEHS/article/view/35371/29783
• Subject:
  Legg-Calve-Perthes disease;;
  Idiopathic avascular necrosis of the femoral head;;
  etiology;
• Identifier: https://apcz.umk.pl/JEHS/article/view/35371
• Data provider:
  Akademicka Platforma Czasopism
• Can I use it?:
  seek permission
• Type:
  text